Researchers conclude that injection of alpha interferon into acupuncture points for the treatment of chronic hepatitis B is more effective than non-specific intramuscular injections or intravenous infusions. Injecting alpha interferon into acupuncture points “showed significantly better effect on the loss of serum HBeAg than intramuscular injection” and “was better than intravenous infusion for loss of serum HBeAg.” HBeAg is an extracellular form of HBcAG, a hepatitis B viral protein that indicates active viral replication. Bloodborne HBeAg is associated with high rates of viral replication and enhanced infectivity. In the study, injection of interferon into acupuncture points was more effective in reducing serum HBeAg than intramuscular injections and intravenous infusions.
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BMC Complement Altern Med. 2012; 12(Suppl 1): P326. doi: 10.1186/1472-6882-12-S1-P326. Acupoint versus non-acupoint injection of antiviral treatment for chronic hepatitis B: a systematic review of randomized controlled trials. J Liu, L Ma, M Han, C Liu, and X Pan.